Intense itching (“pruritus”) and rash caused by an allergic reaction to the louse bites are common symptoms of body lice infestation. When body lice infestation has been present for a long time, heavily bitten areas of the skin can become thickened and discolored, particularly around the midsection of the body (waist, groin, upper thighs); this condition is called “vagabond’s disease.”