Personal character, disposition, and life experience play a role in sexual dysfunction. Fear of intimacy can be a factor in arousal problems. Experiences of abuse, either in childhood or in past or current relationships, can establish a cycle of associating sex with psychological or physical pain. Attempting sexual activity in these circumstances causes more psychological or physical pain. For example, if anxiety prevents lubrication, sexual intercourse can be painful. Conflict, tension, and incompatibility with a sexual partner can cause sexual dysfunction. Depression may be a cause, and stress a contributing factor. Medications, including anti-hypertensives, antidepressants, and tranquilizers are very common causes of sexual dysfunction.