Most cases of sporotrichosis only involve the skin or the tissues underneath the skin. These infections are not life-threatening but must be treated with prescription antifungal medication for several months. The most common treatment for this type of sporotrichosis is itraconazole, taken by mouth for 3 to 6 months. Supersaturated potassium iodide (SSKI) is another treatment option for cutaneous (skin) sporotrichosis. However, SSKI and azole drugs like itraconazole should not be used during pregnancy. Patients with severe forms of sporotrichosis are usually treated with amphotericin B, which is given through a vein. Itraconazole is often used after the initial treatment with amphotericin B, for a total of at least 1 year of antifungal treatment. People with sporotrichosis in the lungs may also need surgery to cut away the infected tissue.
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