Sjögren’s syndrome most commonly affects people aged 40-60, with women accounting for about 90% of cases. It’s difficult to know exactly how many people are affected by the syndrome because many don’t see their GP about their symptoms. The most commonly reported symptoms of Sjögren’s syndrome are a dry mouth and eyes, which can lead to other associated symptoms. However, these symptoms can be common in old age, and most people with dry eyes or a dry mouth do not have Sjögren’s syndrome. Many women also experience vaginal dryness, which can make sex painful.