Throat symptoms may be caused by a wide array of conditions, including infectious diseases, allergies, and gastroesophageal reflux disease (GERD), in which stomach acid backs up into the esophagus. Certain types of head and neck cancers may also cause throat symptoms that include difficulty swallowing, sore throat and the development of throat growths or sores. Because throat symptoms can be due to serious diseases, failure to seek treatment may result in serious complications and permanent damage.