Some people are more susceptible than others to sepsis. Those who are more at risk include: people with weakened immune systems, such as those with HIV, AIDS, or leukemia; young children; older adults; people who use intravenous drugs such as heroin; people with poor dental hygiene; those using a catheter; people who’ve had recent surgery or dental work; those working in an environment with great exposure to bacteria or viruses, such as in a hospital or outdoors.