Chemoradiation is a treatment that combines chemotherapy (cancer-killing medication) and radiotherapy (where radiation is used to kill cancer cells). It’s currently the most effective treatment for anal cancer. You don’t usually need to stay in hospital when you’re having chemoradiation. Chemotherapy for anal cancer is usually given in two cycles, each lasting four to five days, with a four-week gap between the cycles. In many cases, part of the chemotherapy is delivered through a small tube called a peripherally inserted central catheter (PICC) in your arm, which can stay in place until your treatment has finished. The tube means you don’t need to stay in hospital during each of the cycles of chemotherapy. However, you’ll be attached to a small plastic pump, which you take home with you. A few hospitals now offer tablet chemotherapy for anal cancer, which avoids the need for the pump and PICC.