Since Hansen’s disease affects the nerves, loss of feeling or sensation can occur. When loss of sensation occurs, injuries such as burns may go unnoticed. Because you may not feel the pain that can warn you of harm to your body, take extra caution to ensure the affected parts of your body are not injured. If left untreated, the signs of advanced leprosy can include: Paralysis and crippling of hands and feet; Shortening of toes and fingers due to reabsorption; Chronic non-healing ulcers on the bottoms of the feet; Blindness; Loss of eyebrows and Nose disfigurement. Other complications that may sometimes occur are: Painful or tender nerves; Redness and pain around the affected area and Burning sensation in the skin.