As presently, there are no vaccines available against Nipah virus, routine and thorough cleaning and disinfection of pig farms (with appropriate detergents) may be effective in preventing infection. If an outbreak is suspected, the animal premises should be quarantined immediately. Culling of infected animals – with close supervision of burial or incineration of carcasses – may be necessary to reduce the risk of transmission to people. It is also recommended to use sodium hypochlorite (bleach) to disinfect the contaminated areas and equipment. Restricting or banning the movement of animals from infected farms to other areas can reduce the spread of the disease. As Nipah virus outbreaks in domestic animals have preceded human cases, establishing an animal health surveillance system, using a One Health approach, to detect new cases is essential in providing early warning for veterinary and human public health authorities.