Symptoms of Angioedema are that It mostly affects the hands, feet, eyes, lips, or genitals. In severe cases, the inside lining of the throat and bowel can be affected. The swelling usually appears suddenly, and is more severe than normal hives (nettle rash). It commonly lasts 1 to 3 days. There may be a prickling sensation in the affected area before swelling is visible. The swelling is not itchy and the skin may look a normal colour; however, many people with allergic or idiopathic angioedema also develop urticaria (hives), which is red and itchy. As well as visible swellings, angioedema can cause other symptoms, including: a hot or painful sensation in the swollen areas; swelling of the inside of the throat, the windpipe and the tongue, making breathing difficult and swelling of the conjunctiva (the transparent layer of cells that cover the white part of the eye), which affects vision. People with hereditary angioedema may also experience: abdominal (stomach) pain caused by swelling in the stomach and bowel, which can cause nausea, vomiting and diarrhea and swelling of the bladder or urethra (the tube that connects the bladder to the genitals), which can cause bladder problems and difficulty passing urine. Initial symptoms of anaphylaxis include: a feeling of tightness in the chest that leads to breathing problems and swelling of the tongue and throat.